Region-specific preservation of Purkinje cell morphology and motor behavior in the ATXN1[82Q] mouse model of spinocerebellar ataxia 1.

The smaller steps made by the mutant mice could not be explained by a decrease in body weight, as ATXN1[82Q] were on average even a bit heavier that their wild‐type littermates, although this difference did not reach statistical significance (e.g., at 18 weeks: WT: median weight = 21.3 g (interquartile range = 9.4 g), ATXN1[82Q]: median = 26.9 g (interquartile range = 6.9 g), p = 0.778, U = 50.5, Mann–Whitney test).

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