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Anti-PD-1 in Combination With Trametinib Suppresses Tumor Growth and Improves Survival of Intrahepatic Cholangiocarcinoma in Mice.

Cell Mol Gastroenterol Hepatol · 2021 · PMC8413239 · PMID 34033968

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21 In our study, we observed a similar trend in degranulation and IFNγ production of CD8 T cells of trametinib-treated mice, although this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.