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Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction.

Brain · 2021 · PMC8418338 · PMID 34128983

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showed a trendno p-value reported
In contrast, the heat-shock protein mutants (HSPB8 K141N , HSPB1 G84R and HSPB1 P182L ) showed a trend towards a decrease in burst rate, suggesting a hypo-connectivity state.

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