Barely Significant
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Renal hemodynamic effects differ between antidiabetic combination strategies: randomized controlled clinical trial comparing empagliflozin/linagliptin with metformin/insulin glargine.

Cardiovasc Diabetol · 2021 · PMC8418746 · PMID 34481498

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a clear trendno p-value reported
However, in accordance to our data with respect to intraglomerular hemodynamics (see above), there was only a numerical reduction of FF after combined E+L treatment, without reaching significance or showing a clear trend-level, hence not supporting a modulation of presumed hyperfiltration status at single-nephron level.

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