Quantification of myelin damage in the spinal cord using Luxol highlighted around 34% reduction, that however did not reach statistical significance, in the lesion percentage at the injury epicenter in the GW2580-treated group (44.45±8.7 and 29.15±4.8% in untreated and treated groups, respectively, Supplementary Figure 1 C-D ).
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Inhibiting microglia proliferation after spinal cord injury improves recovery in mice and nonhuman primates.
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