Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation.

Theranostics · 2021 · PMC8419052 · PMID 34522221

Europe PMC DOI

hedged sentence

0.2210

closest p · 4.4× alpha

0.2210

boldest claim

The sentences

did not reach statistical significancep = 0.221not close (p > 0.1)

Better spatial learning was associated with an attenuated increase of the TSPO-PET signal during five months of PPARγ stimulation in PS2APP mice (R = -0.733, p = 0.0043, Figure 4 A-B ), but the association did not reach statistical significance in App NL-G-F mice (R = -0.349, p = 0.221, Figure 4 C-D ).

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