Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice.

Nat Commun · 2021 · PMC8421455 · PMID 34489419

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Furthermore, with PLX3397 treatment, response to CO 2 (a vasodilative agent) showed a trend towards impairment (Fig. 7e–f ), suggesting that microglia regulate both blood flow dynamics and are necessary for at least some aspects of vascular reactivity.

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