showed a trendP < 0.05
Four metabolites showed a trend toward overabundance in LAM samples (Mann–Whitney test; P < 0.05) and were subsequently analyzed in plasma from an additional set of 30 LAM patients (Appendix Table S2 ), 12 healthy age‐matched female controls, as well as samples from women with LAM‐related pulmonary diseases, the latter group comprising 10 individuals diagnosed with Langerhans cell histiocytosis, 10 with Sjögren syndrome, seven with emphysema, and three with systemic lupus erythematosus.