Slices obtained from older animals showed a trend toward higher spontaneous activity levels ( Figure 3A , Figure 3—figure supplement 1A, B ) and significantly lower mitochondrial motility than slices obtained from younger animals ( Figure 3B , Figure 2—figure supplement 1A, B ).
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Activity-dependent regulation of mitochondrial motility in developing cortical dendrites.
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We find that there are indeed highly significant differences between the investigated conditions.