LV diastolic dysfunction as assessed by E/E’ showed a trend towards improvement in inactive disease group, a significant improvement was reported by Bruch C et al. 8 Flow mediated dilatation of brachial artery was significantly less in disease active patients as observed by Brevetti G et al. 3 The precise mechanism of endothelial dysfunction in acromegaly is not well understood.
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Acromegaly: Cardiovascular risk factors, cardiovascular manifestations and early vascular alterations in relation to disease activity.
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