Xanthine dehydrogenase as a prognostic biomarker related to tumor immunology in hepatocellular carcinoma.

Cancer Cell Int · 2021 · PMC8425161 · PMID 34496841

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a positive trendno p-value reported

Although there was a significant positive correlation between XDH expression and macrophage infiltration in the TIMER database, only a positive trend was found between XDH expression and CD68 + macrophage infiltration in this small group of HCC tissues.

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a negative trendno p-value reported

Furthermore, a negative trend was also observed in T cell immunoglobulin and mucin domain-containing protein 3 (TIM3) and lymphocyte-activation gene 3 (LAG-3) (Fig. 4 B).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.