Apoptosome Formation through Disruption of the K192-D616 Salt Bridge in the Apaf-1 Closed Form.

ACS Omega · 2021 · PMC8427654 · PMID 34514227

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showed a trendno p-value reported

The K192E mutant showed a trend toward increased caspase activity over WT Apaf-1, but the increase did not reach statistical significance.

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