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Allele-specific mitochondrial stress induced by Multiple Mitochondrial Dysfunctions Syndrome 1 pathogenic mutations modeled in Caenorhabditis elegans.

PLoS Genet · 2021 · PMC8428684 · PMID 34449775

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Surprisingly, mRNA expression of each of these genes trended towards an increase in the Gly166Cys mutant but did not reach statistical significance ( Fig 4A ).

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