Autoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma.

J Exp Med · 2021 · PMC8429038 · PMID 34495298

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0513

boldest claim

The sentences

highly significantP < 0.0001actually significant

This PBC-associated delay in CCA growth was highly significant (P < 0.0001, mixed-effects model) compared with control and PSC mice, with some tumors that even failed to develop in several (five out of nine) cases ( Fig. 3, C and D ; and Fig.

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a clear trendP = 0.0513so close (0.05 < p ≤ 0.1)

Blockade of IFNγ showed a clear trend of a compromised PBC-elicited protection (P = 0.0513; Fig. 7, B and E ), and a similar, significant (P = 0.0165) effect was observed for IL4 blockade ( Fig. 7, C and F ).

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a trend toward significanceno p-value reported

Exact P values are displayed in the legend when 0.13 > P ≥ 0.05 to illustrate a trend toward significance.

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