Hostility in medication-resistant major depression and comorbid generalized anxiety disorder is related to increased hippocampal-amygdala 5-HT_2A receptor density.

To evaluate whether any SCL-90-R questionnaire scales were associated with HippAM 5-HT 2A receptor BI (mean = 266.82, sd = 114.09), the partial correlation analysis (controlled for age: mean = 45.74, sd = 9.78) including all MRD patients showed a nearly significant positive correlation with the SCL-90-R subscale HOS only [(mean = 11.42, sd = 4.30), r (16) = 0.64, p = 0.007].

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