Although, this difference in survival rate did not reach statistical significance (p=0.0769 vs 0.1 μg rF1V x 1) likely due to group size (N=8 in this iteration), the median time to death or euthanasia of the double dose proved to be statistically significant relative to both the single dose and control (PBS) vaccinated mice (p=0.0187 vs 0.1 μg rF1V x 1, p=0.0061 vs PBS).
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Impact of Toll-Like Receptor-Specific Agonists on the Host Immune Response to the <i>Yersinia pestis</i> Plague rF1V Vaccine.
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0.0769