Combined therapy with crizotinib+decitabine or crizotinib+trametinib resulted in a significantly higher inhibition of tumor growth compared to single treatments, while tumors treated with crizotinib+CHO showed a trend toward better inhibition compared to single drugs ( Figure 3 E). 3.4.
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Synergistic Drug Combinations Prevent Resistance in ALK+ Anaplastic Large Cell Lymphoma.
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