Hemodynamics Prior to Valve Replacement for Severe Aortic Stenosis and Pulmonary Hypertension during Long-Term Follow-Up.

Pre-AVR Invasive Hemodynamics of Patients with versus without Post-AVR PH There were substantial and statistically highly significant differences in the key pre-AVR invasive hemodynamic parameters between patients with and without post-AVR PH ( Table 2 , Figure 1 ): patients with post-AVR had higher mean right atrial pressure, right ventricular end-diastolic pressure, mPAP, mPAWP, and PVR, and lower PAC, cardiac index, and stroke volume index than those without.

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There were trends towards lower LVEF and TAPSE, larger indexed left atrial area, more severe mitral regurgitation, and worse TAPSE/sPAP ratio in patients with post-AVR PH compared to those without but these failed to reach statistical significance ( Table 2 ).

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