Phenotypic Expression and Outcomes in Individuals With Rare Genetic Variants of Hypertrophic Cardiomyopathy.

J Am Coll Cardiol · 2021 · PMC8434420 · PMID 34503678

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indeterminate significanceno p-value reported

We analyzed 2 groups of variants found in 8 genes with definitive evidence for HCM ( 3 ): sarcomeric variants P/LP specifically for HCM (SARC-HCM-P/LP) and rare sarcomeric variants of indeterminate significance (SARC-IND) with the potential to cause HCM, dilated cardiomyopathy (DCM), or have little impact on cardiomyopathy risk.

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