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The Toll-Like Receptor 2 Ligand Pam2CSK4 Activates Platelet Nuclear Factor-κB and Bruton's Tyrosine Kinase Signaling to Promote Platelet-Endothelial Cell Interactions.

Front Immunol · 2021 · PMC8435771 · PMID 34527000

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To note, platelets also reduced TNF-α-induced permeability in all experiments, although the data did not reach statistical significance due to experimental variability ( Figure 5E ).

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