Genetic variations of DNA bindings of FOXA1 and co-factors in breast cancer susceptibility.

Nat Commun · 2021 · PMC8438084 · PMID 34518541

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0006

boldest claim

The sentences

highly significantP < 1 × 10 −5actually significant

The interaction effects on breast cancer risk of these five TF pairs were all highly significant ( P < 1 × 10 −5 ; Supplementary Data 2 ).

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showed a trendP < 6.2 × 10 −4actually significant

Overall, we observed that a total of 46 genes (56%) showed a trend of essentiality on cell proliferation, at P < 6.2 × 10 −4 , a Bonferroni-corrected significance level.

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