Proliferation markers reported to be upregulated in cycling β-cells [ Cdc20 , Ccnb2 , AurkB and Cdk1 ( 22 )] trended towards lower expression in old dispersed islet cultures but the differences did not reach statistical significance ( Figure 1D ).
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Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse β-Cells.
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