Predilection for developing a hematogenous orthopaedic implant-associated infection in older versus younger mice.

In younger mice, although there was a trend for increased in vivo BLI signals in the op legs (which increased on day 3 (5.12 × 10 4 ± 2.20 × 10 4 ) and continued to increase through day 21) compared with the non-op legs (which increased on day 3 (1.68 × 10 4 ± 6.62 × 10 3 ) and further increased between days 14 and 28), this did not reach statistical significance ( P = 0.2143) (Fig. 1 a, b).

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