Spermine-Related DNA Hypermethylation and Elevated Expression of Genes for Collagen Formation are Susceptible Factors for Chemotherapy-Induced Hand-Foot Syndrome in Chinese Colorectal Cancer Patients.

Front Pharmacol · 2021 · PMC8440935 · PMID 34539419

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a negative trendno p-value reported

a positive trendno p-value reported

For macrophages M1 and M2, which are the downstream polarization product of M0, M1 demonstrated a negative trend with HFS grade, while M2 showed a positive trend with HFS grade.

also in 4,201 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.