Correlating with this, the CSF biomarker phosoho-tau-181 showed a decreasing trend with Bapineuzumab treatment, however, no difference was observed in Aβ at 78 weeks ( Salloway et al., 2009 ).
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Amyloid-β and α-Synuclein Immunotherapy: From Experimental Studies to Clinical Trials.
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DAD and MMSE tests showed a trend toward improvement in function and cognition between 50 and 78 weeks.