Integrative Network-Based Analysis Reveals Gene Networks and Novel Drug Repositioning Candidates for Alzheimer Disease.

Neurol Genet · 2021 · PMC8441674 · PMID 34532569

Europe PMC DOI

hedged sentence

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closest p · 1.0× alpha

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boldest claim

The sentences

nominally significantp < 0.05actually significant

Step 5: We generate a ranked list of drug repositioning candidates and MOA categories that show enrichment of nominally significant ( p < 0.05) gene-based associations (MAGMA and S-PrediXcan) across compounds within each category.

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