Functional analysis of T cells showed a trend towards fewer polyfunctional (IFN‐γ + TNF‐α + ) T cells in all ΔgL‐MCMV doses as compared to WT‐MCMV (Figure 4b and c ), with no discernible increase in frequencies of polyfunctional T cells after increasing the inoculum of ΔgL‐MCMV.
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Optimal CD8<sup>+</sup> T-cell memory formation following subcutaneous cytomegalovirus infection requires virus replication but not early dendritic cell responses.
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