Myelination induces axonal hotspots of synaptic vesicle fusion that promote sheath growth.

We observed that sheaths longer than 6 μm at 3 dpf showed a trend toward reduced growth in BoNTB-silenced axons ( Figure 5 E), and at 4 dpf there was a significant reduction of sheaths fully grown such that they are flanked by nodes and/or collaterals ( Figure 5 F).

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