Transfusion of ABO non-identical platelets increases the severity of trauma patients at ICU admission.

In the multivariate model, age ( p = 0.021), surgery with neurological intervention (p = 0.006), no surgery ( p < 0.001), APACHEII score ( p = 0.033) and transfusion of ≥10 units of blood products ( p = 0.013) were significantly associated with mortality, while transfusion of ≥3 units of ABO non-identical blood products in the first 24 h of hospitalization and transfusion of ≥1 unit of ABO non-identical cryoprecipitate did not reach statistical significance.

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