Barely Significant
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Improved estimation of time-varying reproduction numbers at low case incidence and between epidemic waves.

PLoS Comput Biol · 2021 · PMC8448340 · PMID 34492011

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a clear trendno p-value reported
Neither APEestim nor EpiEstim recovers a clear trend and both are appreciably worse than even the filtered estimate R ̃ s .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.