Should Postoperative Radiation for Long Bone Metastases Cover Part or All of the Orthopedic Hardware? Results of a Large Retrospective Analysis.

Adv Radiat Oncol · 2021 · PMC8450200 · PMID 34585024

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did not reach statistical significanceno p-value reported

Covariates of time from surgery to RT start, histology of primary tumor (categorized as resistant vs sensitive), intramedullary hardware placement, reaming procedure, and margin status did not reach statistical significance.

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of borderline significanceno p-value reported

Use of intramedullary hardware itself was of borderline significance on univariate analysis, and highly correlated with whole field coverage, making it difficult to provide conclusive evidence supporting hardware seeding micro-metastases.

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