DNA 5-hydroxymethylcytosine in pediatric central nervous system tumors may impact tumor classification and is a positive prognostic marker.

Clin Epigenetics · 2021 · PMC8451154 · PMID 34538273

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

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The sentences

did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)

In a multivariable Cox proportional hazards model adjusted for sex and tumor type, the low total 5hmC group was associated with increased risk of recurrence though this did not reach statistical significance (HR 3.6, CI 95% 0.9–14.5, P = 0.07) and death (HR 3.4, CI 95% 0.69–16.5, P = 0.14).

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