Barely Significant
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Longitudinal retinal layer changes in preclinical Alzheimer's disease.

Acta Ophthalmol · 2021 · PMC8451744 · PMID 33073531

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Another study did demonstrate that Aβ+ individuals had a stronger decrease in macular RNFL, IPL and outer nuclear layer (ONL) volume over a 27‐month time period, but these differences did not reach statistical significance when looking at thickness rather than volume, as we did in our study (Santos et al. 2018 ).

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