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Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m.3243A>G heteroplasmy in iPSC-derived neurons.

Stem Cell Reports · 2021 · PMC8452519 · PMID 34329596

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showed a trendp < 0.05actually significant
In addition, we identified genes important for synaptic vesicle release that were upregulated and showed a trend in the direction of the LH lines (unadjusted p < 0.05), including SNAP25 , SYT4 , VAMP1 , VAMP2 , STXBP1 , SCNA , and SYN1 ( Figure 6 I).

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