Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition.

Indeed, compared with our control NMJ data, we observed that 24 h TubA treatment resulted in a tendency toward an increase in total and multiple contact point NMJ numbers in FUS -ALS P525L co-culture systems, although this did not reach statistical significance ( Figures 7 A and 7B).

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