Subsequently, although the exposure of the ophthalmic artery to 14, 15-EEZE exhibited noticeable vasodilation in comparison to the control vessels, it did not reach statistical significance (reference: 79.65 ± 8.14% vs. 14, 15-EEZE: 103.65 ± 21.26%; Fig. 4 c).
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Cyp2c44 epoxygenase-derived epoxyeicosatrienoic acids in vascular smooth muscle cells elicit vasoconstriction of the murine ophthalmic artery.
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