The exclusion of missense variants with potential aptamer binding effects is evidenced in our study, where SNPs in 96% of nominally significant protein probes associated with COVID-19 also had effects on corresponding gene expression in different tissues across gene expression datasets as curated by our portal ( Open Targets Genetics, 2019 ).
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A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance.
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