According to the overall PCA score plot (Figures 2(c) – 2(f) ), there was a clear trend of separation between the disease and control groups in the positive and negative ion models, indicating significant metabolic differences between the two groups.
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Untargeted Metabolomic Profiling of Cuprizone-Induced Demyelination in Mouse Corpus Callosum by UPLC-Orbitrap/MS Reveals Potential Metabolic Biomarkers of CNS Demyelination Disorders.
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