Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.

Cell · 2021 · PMC8459317 · PMID 34450027

Europe PMC DOI

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nominally significantp = 2.27 × 10 −5actually significant

Even though sample sizes in the East Asian cohorts are small, we observed that 62% of the signals have supportive evidence in East Asian ancestry-only analysis, with the same direction of effect, and 20% of these signals are also nominally significant (binomial test p = 2.27 × 10 −5 , 95% confidence interval [CI] = 7%–100%) ( STAR Methods ).

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