Barely Significant
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Exploring the Photocyclization Pathways of Styrylthiophenes in the Synthesis of Thiahelicenes: When the Theory and Experiment Meet.

J Org Chem · 2021 · PMC8459451 · PMID 33769823

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quite significantno p-value reported
There are four single bonds in each molecule, giving rise to a quite significant amount of 2 4 = 16 conformations by rotation, which finally get reduced by symmetry arguments to 10 nonequivalent molecular conformations (only flat, fully delocalized structures were taken into account at this stage).

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