DNA Intercalators Inhibit Eukaryotic Ribosomal RNA Synthesis by Impairing the Initiation of Transcription.

Genes (Basel) · 2021 · PMC8466728 · PMID 34573394

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quite significantno p-value reported

This effect was quite significant for our positive control (high concentration of ActD), suggesting that compounds can activate the p53-dependent response, which may affect transcription or/and mRNA turnover.

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