Tolerant Larvae and Sensitive Juveniles: Integrating Metabolomics and Whole-Organism Responses to Define Life-Stage Specific Sensitivity to Ocean Acidification in the American Lobster.

In stage II larvae, the same metabolites (fatty acids and citrate cycle intermediates) accumulate under 3000 μatm, with no change in succinate or a clear trend in phospho-L-arginine, but with a trend of increasing lactate concentration, suggesting a transition to anaerobic metabolism.

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