Optimization of Taxol Extraction Process Using Response Surface Methodology and Investigation of Temporal and Spatial Distribution of Taxol in <i>Taxus mairei</i>.

A value of p < 0.05 was considered statistically significant, p < 0.01 was considered statistically highly significant and p < 0.001 was considered statistically extremely significant. 3.

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The accumulation of taxol in twigs and leaves of females (with red aril, FR) was significantly higher than that of males (M); however, the content showed a decreasing trend with the increasing tree ages.

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With the increase of methanol concentration, the taxol yield showed a trend of first increasing and then decreasing.

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