The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension.

The Western blot analysis of total lung lysates showed an upregulation of CD68 and CD163 expression in hypoxic lungs (yet it did not reach statistical significance for CD68) and showed a dynamic toward a partial decrease in CD163+ and CD68+ cell accumulation in response to butyrate treatment of hypoxic animals ( Figure 3 C–E). 2.4.

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