Complement Component C1q as a Potential Diagnostic Tool for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Subtyping.

J Clin Med · 2021 · PMC8467657 · PMID 34575280

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The unexpected finding of a quite significant proportion of ME/CFS cases showing increased levels of C1q and decreased C1 inhibitor (42.8% and 8.8%, respectively) ( Supplementary Table S1 ), together with the C1q deficiency being associated with autoimmune diseases such as systemic lupus erythematosus [ 24 ], motivated our interest to hypothesize C1q as a potential biomarker for ME/CFS subtyping. 3.4.2.

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