Cortical Thinning of Motor and Non-Motor Brain Regions Enables Diagnosis of Amyotrophic Lateral Sclerosis and Supports Distinction between Upper- and Lower-Motoneuron Phenotypes.

While female ALS showed a trend towards higher age-adjusted CTs in the right parieto-occipital and left mid-frontal regions compared to healthy females and males with ALS, males with ALS demonstrated higher CTs in the left lingual and left superior temporal regions compared to healthy males and females with ALS [ 29 ].

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