As we can see in Figure 5 A, the PCA model showed a clear trend of group clustering between the bone marrow (allo-HSCT) transplant group and the control healthy (CT) group, with an absence of outliers.
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High Throughput Analysis Reveals Changes in Gut Microbiota and Specific Fecal Metabolomic Signature in Hematopoietic Stem Cell Transplant Patients.
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Furthermore, a CV-ANOVA test was performed to check the statistical significance of the differences between the two groups in the OPLS-DA model, which resulted in a score of p -value = 3.956 × 10 −12 , indicating that the differences between the groups within the model were highly significant.