Local injury and systemic infection in infants alter later nociception and pain affect during early life and adulthood.

Brain Behav Immun Health · 2020 · PMC8474633 · PMID 34589906

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clearly significantno p-value reported

By adulthood, this aversion to the painful stimulus was clearly significant, and most prominent in those pups exposed to both inflammatory injury and systemic infection early in life.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.