27 Despite the proven benefits of statins, the data from the SPARCL (Stroke Prevention by Aggressive Reduction of Cholesterol Levels) trial showed a trend toward an increased rate of ICH with statin therapy. 28 However, a post hoc analysis revealed that the highest risk was linked to previous hemorrhagic stroke, and there was no relationship between ICH and low‐density lipoprotein cholesterol levels. 29 , 30 In the present study, we found that statin therapy was associated with a lower risk of ICH.
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Intracranial Bleeding After Percutaneous Coronary Intervention: Time-Dependent Incidence, Predictors, and Impact on Mortality.
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