Chronic Distress in Male Mice Impairs Motivation Compromising Both Effort and Reward Processing With Altered Anterior Insular Cortex and Basolateral Amygdala Neural Activation.

Front Behav Neurosci · 2021 · PMC8475760 · PMID 34588963

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A negative trend of reduced FosB-labelled cells density was also evidenced in the dorsal BNST [VEH: 337.41 ± 29.97; CORT: 227.11 ± 29.81] ( Z = 1.9, p = 0.05) and the VTA [VEH: 342.43 ± 26.04; CORT: 249.05 ± 41.85] ( Z = 1.6, p = 0.10) of CORT-treated animals.

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